Environmental Health has published in its April 2014 edition the Columbia SRP paper, "A cross-sectional study of well water arsenic and child IQ in Maine schoolchildren." CU SRP Project 2 scientist Gail Wasserman is the lead author. Her Columbia collaborators include Xinhua Liu, Nancy J LoIacono, Jennie Kline, Pam Factor-Litvak, Alexander van Geen, Jacob L Mey, Diane Levy, and Joseph H Graziano. Richard Abramson formerly with Readfield ME Public Schools and Amy Schwartz at the University of New Hampshire also contributed to this paper.
The authors start with a description of past studies. Earlier research by the CU SRP team focused on dose-dependent adverse associations between consumption of arsenic (As)- contaminated water from household wells and intellectual function in young Bangladeshi children. Their initial work with 6- and 10-year olds, after adjustment for social factors related to intellectual function, indicated that water arsenic concentration (WAs) was significantly negatively related to WPPSI-III and WISC-III Performance (nonverbal ability) scores, but, in most instances, not to other components of intelligence, such as Verbal scores. A more recent study of Bangladeshi 9-10 year olds, resulted in marginally significant associations between WAs and both Verbal Comprehension and Working Memory scores from the WISC-IV, after adjustments for socio-demographic features and for co-occurring exposure to manganese in drinking wate. Water Arsenic was unrelated to other aspects of intellectual functioning. These and other studies in different populations have suggested that As exposure may affect early development. However, there has been little consistency in the specific components of child intelligence most affected.
The CU SRP study described in this paper included 272 childrent in grades 3-5 in 3 Maine public school districts. It examined associations between drinking water Arsenic and intelligence as measured by the WISC-IV test. The findings suggest that levels of Water Arsenic equal or greater than 5 mug/L, levels, which are below EPA national standards and occur frequently in some US regions, could pose a threat to child development.
Wasserman Gail A, Liu Xinhua, LoIacono Nancy J, Kline Jennie, Factor-Litvak Pam, van Geen Alexander, Mey Jacob L, Levy Diane, Abramson Richard, Schwartz Amy, Graziano Joseph H. A cross-sectional study of well water arsenic and child IQ in Maine schoolchildren. Environmental Health 2014, 13:23 (1 April 2014). DOI: 10.1186/1476-069X-13-23